Intended for healthcare professionals


Sixty seconds on . . . frostbite

51app 2024; 384 doi: (Published 16 February 2024) Cite this as: 51app 2024;384:q422
  1. Jacqui Wise
  1. Kent

Is this the latest Frozen sequel?

Not quite. The US Food and Drug Administration (FDA) has approved the first treatment option for severe frostbite—iloprost (Aurlumyn) injection.1 This new option “provides physicians with a tool that will help prevent the life changing amputation of one’s frostbitten fingers or toes,” said Norman Stockbridge, from the FDA’s Center for Drug Evaluation and 51app.

Snow joke

Indeed. Iloprost is a vasodilator and prevents blood from clotting. It was originally approved in 2004 in the US for the treatment of pulmonary arterial hypertension. The treatment received priority review and …

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